PCR Cycle Models

Automated DNA replication using the polymerase chain reaction (PCR) allows scientists to make multiple copies of DNA inside a test tube. Modeling PCR cycles helps students practice base-pairing rules, appreciate and apply exponential numbers, and understand the roles of the components involved in DNA replication. The models can help teachers assess student readiness for class lab experiences with PCR.

Grades covered: 7 through 12
Curriculum Topics: Base-pairing, Biotechnology, DNA replication, Exponential functions (applied), Forensics

Standards

Idea Sheets are cross-referenced to subjects listed in the Common Core, Next Generation Science Standards, and California Content Standards.

Common Standards Click to View

NGSS DCI(s): Inheritance of Traits, Variation of Traits, Natural Selection, Evidence of Common Ancestry and Diversity; Common Core Mathematics: Building Functions

California Standards (Click to View)

5.b. How to apply base-pairing rules to explain precise copying of DNA during semi-conservative replication, and transcription of information from DNA into mRNA.||Grade 9-12||03. Biology/Life Sciences||2. Genetics||5. The genetic composition of cells can be altered by incorporation of exogenous DNA into the cells.|||5.c. How genetic engineering (biotechnology) is used to produce novel biomedical and agricultural products.||Grade 9-12||03. Biology/Life Sciences||2. Genetics||5. The genetic composition of cells can be altered by incorporation of exogenous DNA into the cells.

Categories include:
  • Life Science
  • Grades 6-8
  • Science
  • Math
Tags: Structure & Function, Heredity, Chemical Reactions
Subjects covered: Life Science, Math